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HIV: The Basics

HIV: The Basics

A concise explanation of HIV/AIDS

HIV (Human Immunodeficiency Virus) is a retrovirus that can be transmitted between people by unsafe sexual contact, if at least one person is infected with HIV. In infected humans, the HIV-virus enters cells that express the cell surface protein CD4 and co-receptors CCR5 and/or CXCR4. When this virus enters the cell, it converts the genetic information of HIV (or RNA) into DNA with reverse transcriptase. The DNA is then incorporated in the host cell’s chromosome and can subsequently be replicated and used to make viral proteins (see figure below). When there are enough copies of the virus, the host cell bursts open releasing the viruses to find new host cells and the host cell dies.

hiv, aids, cells, autoimmune, CXCR4, viral infection, CD4, CD5

The most common victim of HIV is the CD4 T cell and the number of these cells decline during HIV infection. Because CD4 T cells are essential for the functioning of the immune system, this decline is the main reason for the weakened immune system of the HIV-patients. As a consequence, late-stage HIV-patients are susceptible to infections that are harmless in healthy humans. The most advanced stages of HIV-infection are generally known as AIDS (Acquired Immunodeficiency Syndrome).

Symptoms

The first symptoms occur shortly after the HIV-infection. Patients usually display symptoms like a sore throat, fever and a blotchy red rash. These early symptoms last up to three weeks and are commonly diagnosed as flu or a mild viral infection. After that, the HIV-infection can stay without symptoms for many years before the patient’s immune system will start to get significantly weaker. Common symptoms of a more advanced HIV-infection and AIDS are swollen lymph nodes, recurring herpes and weight loss.

Prevention and treatment

To prevent HIV infection from entering the AIDS stage, quick diagnosis and adequate treatment is needed. New diagnostic tools are able to detect HIV a month after infection, even before the patient expresses HIV-specific symptoms. If an infection is picked up on early, the doctor will regularly check the CD4 T cell count in the blood. One of the common treatments is the so-called antiretroviral therapy (ART). This therapy prevents common symptoms of HIV by slowing down the replication of the HIV virus.

Read the interview with Prof. Mancini about improving HIV treatment with computer simulation.

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81 Comments

  • Bright
    January 11, 2017, 17:25

    MUST READ: HOW I GOT CURED FROM MY HIV VIRUS)

    Hello, My name is Bright Gibson, I was diagnosed of HIV and I have tried all possible means to get cure but all to no avail, until i saw a post in a health forum about a herbal doctor from West Africa ( Dr AGEGE ) who prepare herbal medicine to cure all kind of diseases including herpes virus, at first i doubted if it was real but decided to give it a try, when i contact this herbal doctor via his email, he prepared a herbal medicine and sent it to me , when i received this herbal medicine, he gave me step by instructions on how to apply it, when i applied it as instructed, i was cured of this deadly virus HIV within a week of usage I am now free from the virus, i was tasted negative. He can also cure any type of disease and can bring back your Ex partner to you, you are to Contact this great herbal doctor via his email ( dragegespellalter@yahoo.com) or call or whatsapp him with his number +2349036492096, when you contact him, make sure you tell him that i referenced you, i’m happy he save my life

    REPLY
  • deanfneilsarah
    January 17, 2017, 21:38

    Hello!! I’m indeed very happy for the great help that Dr. okorom rendered to me, I was a herpes patient my husband also was a herpes patient, we saw a blog whereby Dr. okorom cured herpes, we (Me and My Husband) decided to contact him which we did, he asked us to buy some items, unfailingly we sent him the money he will need in buying the items required, He castes the spell and asked us to go for check-up after three days of casting the spell, Luckily for us we were tested herpes negative, now I believe all these Testimonies about him on the internet, he is truly a great man, if you want to discuss with me on how he cured us, kindly email me on deanfneilsarah@gmail.com or you can contact the great Herbalist and a spell caster on dr.okoromspellhome@live.com or you can call him via his mobile phone number on +2348158168556,,…

    REPLY
  • stefann
    February 28, 2017, 16:13

    Unbelievable but true!! I was diagnosed with HIV this year, and for some reason my mind was ready for that answer since I had been showing strange signs since January of this year. Both my love were there with me when I got the news and we are both very supportive, and I am truly thankful for that. I told my closest friends, one of them being the girl I really like, and she has been supporting me since I started this whole process and has always given me support. So far no one has turned their back on me due to ignorance or anything like that. I am thankful that I have not fallen into a depression or anything like that. On Monday August I get my result for CD4 (T-cell) count and virus load count, and I am hoping I have a high level of T-cells. The last thing I have lost is hope and that was what lead me to Dr Lucky of ( homeofnaturalremedy@gmail.com) Who helped me with herbal herbs medicine to get me cured of this disease, and I would like to let others know that even though sometimes we might feel the world is going to come down on us, there will always be someone we can count on, who will support us and love us. I am not in a support group at the moment but I would love to be in one, meet others and share with them my testimony. This is not the end of the world; this is not a reason to give up on our hopes and dreams. We are in control, not the disease. Contact him:( homeofnaturalremedy@gmail.com ) or call +2349050606649 as I am right now, I am grateful.

    REPLY
  • mrs elizabeth
    March 29, 2017, 21:13

    I am from New York. I was in trouble when doctor told me that I have been
    diagnosed Hiv with … I though about my Family, I know my Family will
    face a serious problem when I’m gone, I lost hope and I wept all day, but one
    day I was surfing the Internet I found Dr. Emmanuel contact number. I called him
    and he guided me. I asked him for solutions and he started the remedies for my
    health. Thank God, now everything is fine, I’m cured by Dr. Emmanuel herbal
    medicine, I’m very thankful to Dr. Emmanuel and very happy with my hubby and
    family. email him on traditionalherbalhealingcentre@gmail.com OR contact his number:
    +2348110857969
    DOCTOR EMMANUEL CAN AS WELL CURE THE FOLLOWING DISEASE:-
    1. HIV/AIDS
    2. HERPES
    3. CANCER
    4. ALS
    5. DIABETES
    6. HEPATITIS……………………………………

    REPLY
  • agnes machili
    April 2, 2017, 11:09

    Thanks dr abiola for good work for healing my brother for HIV sickness I was very sick for a year + and my daddy have to spend so much money on medical care and drug I have been taking to some many place for healing … even different pastor have pray For him it get worse every 6hous the man that heal with 45mins is here the man that the lord god have given the power to put every thing in place the man that gives a word and never fails my kid brother was just chatting one day when he See this post of mayra about the curing of HIV virus by DR Abiola I run to my daddy and tell him about the man my daddy decided to call him and confirm it if it is true about the cure the man just assure him about his work Hepatitis B, ALS, MND, Epilepsy, Leukemia, Asthma, Cancer, HIV, Herpes etc, at first i doubted if it was real but decided to give it a try , When i contact this herbal Dr.ABIOLA via his email: deadly.disea Ses.cure@hotmail.com, and my daddy explain him problem to him and he told my daddy that he is going to prepare herbal medicine and sent it to me, when my daddy received this herbal medicine portion, he gave me step by Step instructions on how to use it, when my brother applied it as instructed, in 14 days, so my brother went to check up and he was cured of this deadly disease within 2 weeks, he is now cure and free from hiv. All thanks to Dr.ABIOLA. Contact this great herbal cure via his email deadly.diseases.cure@hotmail.com or webs sit deadlydiseasescure.webs.com or call him on +2348100609098

    REPLY
    • Crystal Grham@agnes machili
      September 27, 2017, 00:07

      Hello everyone this is my first visit to this blog and I want to share my life experience here how I was cured of my HIV by Dr Destiny to herbalist with his herbal medicine God bless him for the good work he is very doing and if you have Any sickness, disease or virus that you think its the end for you quickly contact him now for email: drdestinyspellhome@gmail.com or Call / Whatsapp number +2348105074556 God we bless you Dr Destiny

      REPLY
      • Marry Vera@Crystal Grham
        October 6, 2017, 05:45

        HELLO, i have read testimonies about this great man called Dr Destiny how he helped people to get pregnant and also help people to cure HIV with his herbal medicine, so i decided to give him a try, i am here today to give my own testimony on how this great man helped me to cure my HIV disease and also helped my sister to get pregnant, i just told him and he said he was going to work on it miraculously and in a short period of time i was lifted from these terrible disease. And it took my sister just a week to get pregnant after he was done. Contact this great man and He will help you no matter the the problem you are facing. Email him at drdestinyspellhome@gmail.com call +2348105074556 ..

        REPLY
        • Marry Vera levo@Marry Vera
          October 6, 2017, 05:48

          HELLO, i have read testimonies about this great man called Dr Destiny how he helped people to get pregnant and also help people to cure HIV with his herbal medicine, so i decided to give him a try, i am here today to give my own testimony on how this great man helped me to cure my HIV disease and also helped my sister to get pregnant, i just told him and he said he was going to work on it miraculously and in a short period of time i was lifted from these terrible disease. And it took my sister just a week to get pregnant after he was done. Contact this great man and He will help you no matter the the problem you are facing. Email him at drdestinyspellhome@gmail.com call
          +234 810 507 4556

          REPLY