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HIV: The Basics

HIV: The Basics

A concise explanation of HIV/AIDS

HIV (Human Immunodeficiency Virus) is a retrovirus that can be transmitted between people by unsafe sexual contact, if at least one person is infected with HIV. In infected humans, the HIV-virus enters cells that express the cell surface protein CD4 and co-receptors CCR5 and/or CXCR4. When this virus enters the cell, it converts the genetic information of HIV (or RNA) into DNA with reverse transcriptase. The DNA is then incorporated in the host cell’s chromosome and can subsequently be replicated and used to make viral proteins (see figure below). When there are enough copies of the virus, the host cell bursts open releasing the viruses to find new host cells and the host cell dies.

hiv, aids, cells, autoimmune, CXCR4, viral infection, CD4, CD5

The most common victim of HIV is the CD4 T cell and the number of these cells decline during HIV infection. Because CD4 T cells are essential for the functioning of the immune system, this decline is the main reason for the weakened immune system of the HIV-patients. As a consequence, late-stage HIV-patients are susceptible to infections that are harmless in healthy humans. The most advanced stages of HIV-infection are generally known as AIDS (Acquired Immunodeficiency Syndrome).

Symptoms

The first symptoms occur shortly after the HIV-infection. Patients usually display symptoms like a sore throat, fever and a blotchy red rash. These early symptoms last up to three weeks and are commonly diagnosed as flu or a mild viral infection. After that, the HIV-infection can stay without symptoms for many years before the patient’s immune system will start to get significantly weaker. Common symptoms of a more advanced HIV-infection and AIDS are swollen lymph nodes, recurring herpes and weight loss.

Prevention and treatment

To prevent HIV infection from entering the AIDS stage, quick diagnosis and adequate treatment is needed. New diagnostic tools are able to detect HIV a month after infection, even before the patient expresses HIV-specific symptoms. If an infection is picked up on early, the doctor will regularly check the CD4 T cell count in the blood. One of the common treatments is the so-called antiretroviral therapy (ART). This therapy prevents common symptoms of HIV by slowing down the replication of the HIV virus.

Read the interview with Prof. Mancini about improving HIV treatment with computer simulation.

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16 Comments

  • […] What would happen if we could predict the dynamics of viral infections, such as HIV, in human subjects? Similarly, what would happen if we could model the behavior of the host’s immune system and the effect of therapy? A new groundbreaking computational model might be able to do just that. Using this model could change the contemporary view on viral infections and how one should treat them. If you first want to read up on HIV/AIDS, read this background article. […]

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    • Hey, I’m Gloria Mark from USA, I never imagined herbal remedy could treat DEPRESSION until i read and meet an African herbalist online named Dr White. I read a lot of people commending him of being able to cure HIV, HERPES and other deadly diseases. I wrote him because my nice was suffering from what the physicians called acute and severe depression. After taking her to several psychiatrists, she had several sections of psychotherapy and several drugs administered including antidepressants but she never recovered. With little conviction but determination to end her suffering I wrote Dr White but a week intake of Dr White’s herbal remedy did the magic and today she’s perfectly ok and back to work, should you have or know anybody with DEPRESSION or HIV please contact this great healer on drwhitethehivhealer@gmail.com or watsapp +234(0)9091844595. I bear witness you will not regret doing so because I take it on me to tell the world about this.

      You may reach me on: markgloria80@gmail.com

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      • Johnson Kings@Johnson Kings
        March 2, 2018, 23:22

        hey guys, the above is a testimony from another beneficiary of doc White’s miracle. dont chain your self to Aids

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  • calif
    March 1, 2018, 14:41

    Hello everyone out there i have a very important story to share with you about my pass live that makes me a very happy man today to come hare start talking about it, I am Calif from USA, am very happy to share this great news about a great and powerful DR frank who cured me of blood cancer that almost take my life. I suffered this illness for 5 years I could not find a cure i do nothing but cry
    day by day on till one day I was working on something online when I saw a blog where a woman was showing a powerful DR performance online how he help her with the cure of HIV i have no choice at that time to dough anything but believe everything that come my way to i have to take he contact and contacted him for helped she also mentioned that this same Man can also cure any Cain of disease with herbal medicines, without wasting more time I contacted him in his email
    (drfrankhealinghome104@gmail.com) and explained all my problems to him. He told me not to worry about what is already done that he we help me at first i see it as joke, He said that is going to prepare an herbal medicine and that He would send it to me. the Dr said the use of herbal medicine according to their requirements can do a lot for any seek one out a lot, and I started using it before I knew I felt changes in me, two weeks later, I went to the hospital for a medical checkup and to my surprise I was completely cured of the blood cancer. I am very happy smile that I am free from disease, all thanks and gratitude to God and DR frank. If you are outside suffering from herpes, HIV, cancer, diabetes, low spam cam need kids,marriage problems, asthma, brain fog or any kind of illness, quickly contact this powerful man by email (drfrankhealinghome104@gmail.com) and whats app number +2348025760554

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  • linda eggers
    March 8, 2018, 09:23

    Greetings to the general public, i want to tell about how i was cured of HIV/AIDS disease by a Doctor called Dr Agbebaku. I was browsing through the Internet searching for remedy on HIV and i saw comment of people talking about how Doctor Agbebaku cured them. I Was scared because i never believed in the Internet but i was convince to give him a try because i having no hope of been cured of HIV/AIDS so i decided to contact him with his email that was listed on the comment dragbebakuspellsolutiontemple@gmail.com when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my HIV result came out negative. I pray for you Dr Agbebaku God will give you everlasting life, you shall not die before your time for being a sincere and great men. Am so happy, you can also contact him if you have any problem E-mail him dragbebakuspellsolutiontemple@gmail.com or Add him up on WhatsApp +2349053099479 or call +2349035850834 .

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  • Stella Marris
    March 9, 2018, 21:38

    Hello everyone here in this forum i am so glad that i have this great opportunity to come out here and share my testimony on how Dr idahosa was able to cure me totally from Hiv disease, i have been suffering from this Disease for approximately 4 Years now, i have tried various ways to get rid of this Virus out of my body, i have also purchase for Medical treatment from my doctor but they all failed, sometime back now while i was browsing the Internet i found some good quote concerning Dr idahosa Herbal Medicine, and how he has been using it to save souls from Different Disease including Cancer, someone also said she was been cured of Hiv from his medicine, and they gave out his contact details in case anyone needs his help, i decided to contact Dr idahosa and i told him about my Hiv illness he told me not to worry that he was going to send me his herbal medicine all i was to do is to send him my personal details and also my home address so he can post the Medicine to me, actually i did all that was required by this Man, i took the medicine just as prescribe by him, he told me to go for check up in the hospital which i did and to my great surprise my Doctor told me the Hiv Virus was no longer there, i even went to other hospital for better confirmation its was still the same thing, Today i am so happy that i am Negative again, Dr idahosa has given me reasons to share tears of Joy, you can reach to Dr idahosa on his email address at ( dridahosasolutioncenter@gmail.com) or call him on +2348134261542

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  • stephine
    March 10, 2018, 22:40

    MY HIV HEALING TESTIMONY

    My mouth is short of words, i am so happy because Dr voodoo has healed me from HIV ailment which i have been suffering from the past 5years now, i have spend a lot when getting drugs from the hospital to keep me healthy, i have tried all means in life to always i can become HIV negative one day, but there was no answer until i found Dr voodoo the parish of African who provide me some healing spell that he uses to help me, now i am glad telling everyone that i am now HIV Negative, i am very happy, thank you Dr voodoo for helping my life comes back newly without any form of crisis, may the good lord that i serve blessed you Dr voodoo and equip you to the higher grade for healing my life. i am so amazed. so i will announced to everyone in this whole world that is HIV positive to please follow my advice and get healed on time, because we all knows that HIV disease is a deadly type,contact Dr voodoo for your HIV healing spell today at: voodoospelltemple66@gmail.com He will be always happy to assist you online and ensure you get healed on time, contact Dr voodoo today for your healing spell immediately, you can also add him on whatsApp +2349061243458 thank you sir.

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